A comedy/drama about four friends from high school who start hanging out again after one of them finds out he is a father. They each deal with their own problems, and their stories overlap and affect each other.
You are going to run in problems and misunderstanding with such title.
The main drawback however is that it gives me absolutely no clue what it is about.
So what it is about?
I've decided against it already, but to address the valid point you make, not every title, I'd even argue so far as to say most titles do not give you any idea what the film is about.
If you had no idea what Scarface was about, would the title help explain it? I don't think so.
What about any title that uses a character's name?
I think I'm going with a different title
"Guys With Issues"
or "Dudes With Issues"
Something like that