This is just how I do it, so it not definitive.
Firstly, when I'm location scouting I measure all the spaces and create floorplans. Usually I'll walk through the action myself at this point, look at potential camera positions and take digital stills from those positions, marking them on my rough floor plan.
I always book a hall for a three or four days rehearsal before going onto location. In this hall I mark up my locations on the floor (think of Dogville, you'll get it) and use these spaces to rehearse the actors. Part of that reheasal process will involve a rough blocking of the scene. That is, having the actors decide where and when they are going to stand/sit/move/leap onto tables etc. I then check my rough camera positions around the scene as it plays in reheasal and make alterations and notes. Reworking those notes into a floorplan in my production file.
This means when I arrive on location we just adapt the existing blocking and play of the scene to the actual conditions and because I've worked from a tape measure and photos we're normally spot on.
This means on location I follow this formula
1) Go over the floorplans and storyboard for the scene with the DP and sound, talking them though the action (This is done whilst the actors are being brought onto the set.)
2)Get the actors to run the scene, adapting their reheasal blocking to the space whilst the DP and sound watch the action, make minor adjustments to the blocking, discuss if we need to make any adjustments to the shooting scheme as a result.
3) If everyone is happy with how the scene plays, the camera team sets up in the first position and I use that time to rehearse the actors. This is where the days we spent working the script pays off, because lots of actors don't even start to understand lines until they're in the context of the action. By the time my actors hit the set they have not only done that work, but also had a few days to process that and think about the scene. When it comes to the "on set" rehearsals we're actually doing detail work rather than basic character development work.
4) When the first camera position is set we run a camera rehearsal, make any last minute adjustments and give the boom operator a chance to find the best position and rehease their movements.
5) Go for a take.
I hope this has helped. But, like I said, it's just how I do it. I just know that I get better work form my actors and a faster turnaround on my set ups by doing most of the blocking and rehearsal of the scene before I get anywhere near the set. Preparation and planning is everything. The other strenght of working from floorplans is that you can see your coverage easily and make rapid adjustments to your game plan, if circumstances force you to.