See below.
It can be good, it can be bad. It can really depend on your film, the appropriate target market, what regions your genre does well, whether those attachments will scare your target audience away, attract your audience, or even worse, make your audience not care. It'll also depend on your budget level and what your goals for your film are. If you're just trying to get runs on the board and don't care whether your final film is marketable or able to attract finance then your attachments may not matter. The right attachments are great, the bad attachments are the kiss of death for a project, especially if you're looking at either financing for your film or distribution for your film.
Those mid level roles is where you can bolster appeal in specific international regions that are likely to purchase your film, perhaps even allow their arms to be twisted for pre-sales. Casting the wrong person in the wrong role could cost you 7 figures if you find yourself with a run-away success.
That all being said, I'm going to guess that this is your first rodeo, so not everyone is going to be able to afford or even get all the right people.
A great casting director can help guide you.