Will a distributor take on just one single DVD release OR do they only want to do deals with studios that have a constant flow of releases?

Well i don't have agreements with studios to take on loads of releases.

You will find if a distributer likes the film they will take it on regardless of the context.

Any distributor will look at any film... they never want to be the one who misses the next big thing.

Some sales agents will package films for distributors to make a better deal and if your film is weaker it may get included in this. It's never a bad thing as the film will get released. You will however get a little screwed on the money side if yours if the weaker one...